Dr. Cillian O’Beirne
Post-Doc
Chimie ParisTech
PSL University
CNRS
Institute of Chemistry for Life and Health Sciences
Laboratory for Inorganic Chemical Biology
+33 1 85 78 41 53
cillian.o-beirne@chimieparistech.psl.eu
Cillian was born in Dublin, Ireland, in 1990, and began his chemistry education in Maynooth University, where he achieved a BSc in Pharmaceutical and Biomedical Chemistry, followed by a Masters in Chemistry from University College Dublin in 2015. After a short research internship, Cillian was awarded a dual scholarship to undertake a PhD with Dr Matthias Tacke, in University College Dublin, where he expanded the topic of using N-heterocyclic carbene silver complexes as resistance breaking antimicrobials; during his time here he furthered research in the field by successfully creating a continuous flow process for the synthesis of these compounds.
Directly after the completion of his PhD in 2020, Cillian moved to undertake a short post-doctoral position with the research group of Prof. Dr. Ingo Ott in Technische Universität Braunschweig. During his short stay he worked on designing metallodrugs for use against the SARS-CoV-2 virus, while helping to establish an antimicrobial testing suite to be used in future projects by the research group.
Cillian moved to Paris in April, 2021, and works with the Groups of Dr Gilles Gasser and Dr Kevin Cariou as a Post-doctoral researcher to design metallocene antifungal compounds for target neglected tropical diseases.
In his spare time Cillian likes to watch and play football, generally try to stay active and explore every inch of Paris that he can. On quieter days, he passes the time reading books of all kinds, playing games and desperately tries to become fluent in French.
Awards
2019: 1st Prize Poster presentation; RSC Coordination and Organometallic Discussion Group meeting, University College Dublin
2016: School of School of Chemistry research scholarship
2016: College of Science PhD research scholarship
Publications
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- Continuous flow synthesis and antimicrobial evaluation of NHC* silver carboxylate derivatives of SBC3 in vitro and in vivo, Cillian O’Beirne, Magdalena E Piatek, Jen Fossen, Helge Müller-Bunz, David R Andes, Kevin Kavanagh, Siddappa A Patil, Marcus Baumann, Matthias Tacke; Metallomics, 2021, 13, DOI: https://doi.org/10.1093/mtomcs/mfaa011.
- Synthesis, structures and antimicrobial activity of novel NHC*- and Ph3P-Ag (I)-Benzoate derivatives, Cilian O’Beirne, Nada. F. Alhamad, Qinxi Ma, Helge Müller-Bunz, Kevin Kavanagh, Geraldine Butler, Xiangming Zhu, Matthias Tacke; Inorg. Chim. Acta, 2019, 486, 294–303.
- Novel derivatives of the antibiotic NHC–Ag(I) drug candidate SBC3: Synthesis, biological evaluation and 109Ag NMR studies, Cillian O’Beirne, Hessah T. Althani, Oyinlola Dada, Jennifer Cassidy, Kevin Kavanagh, Helge Müller-Bunz, Yannick Ortin, Xiangming Zhu, Matthias Tacke; Polyhedron, 2018, 149, 95–103.